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The principal cytochrome P450 isoenzyme associated seems to become CYP2E1, with CYP1A2 and CYP3A4 as more pathways. Approximately 85% of an oral dose seems from the urine inside 24 several hours of administration, most since the glucuronide conjugate, with compact amounts of other conjugates and unchanged drug [see OVERDOSAGE] for toxicity informat